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OCR: al iodine Toxic adenomas have a low intrathyroid o the pool and preferentially secrete T3. Prior the development of frank hyperthyroidism. d hormoneadenoma may secrete just enough thyro onse to to lower TSH and suppress the TSH resp oma. TRH - the so-called subclinical toxic ader dine Toxic adenoma may be treated by radioic dule and therapy, or by surgical removal of the no n rendered the affected lobe, after the patient has be euthyroid with antithyroid drugs.